Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat

Abstract Fusarium head blight (FHB), mainly caused by graminearum , is one of the most devastating diseases in wheat and barley worldwide. In addition to causing severe yield losses, F. produces deoxynivalenol (DON), a trichothecene mycotoxin which harmful human health serves as an important virulence factor. Currently, changes global climate tillage systems have made FHB epidemics more frequent severe. During past decade, considerable efforts been deployed reveal pathogenic mechanisms identify resistance genes wheat, breed FHB-resistant varieties. this review, we highlight recent advances pathogenesis, F . -wheat interaction, defense mechanisms. This review contains four main sections: (1) signal sensing transduction associated with pathogenesis ; (2) regulation functions DON during infection; (3) roles -secreted enzymes effectors facilitating pathogen infection wheat; (4) components involved interactions A comprehensive understanding molecular between will contribute development novel efficient strategies for controlling FHB.